148090_8916When Grey’s Anatomy started life as a midseason replacement for ABC in the Spring of 2005, it debuted without much fanfare and with little hope of long-term survival. Not only did it survive, it thrived — now in its 14th season, Grey’s is about to hit a major milestone: Its 300th episode. Creator Shonda Rhimes admits she had no idea how big or how socially powerful her show would become. All she wanted to do, she says, was tell interesting stories. (Click on the media bar below to hear Shonda Rhimes)

Grey’s Anatomy celebrates its 300th episode this Thursday night at 8/7c on ABC.

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