It’s that time of year again – Labor Day – and that means Jerry Lewis is hosting his annual Muscular Dystrophy Telethon for the 44th time. The legendary performer, who is the MDA National Chairman, is headlining the event with a host of celebrities expected to join in on the fundraiser. And a few names were recently added to the roster.

Lynyrd Skynyrd, The Grascals and The Roys are set to perform, joining previously announced names including David Archuleta, Enrique Iglesias, WAR, John Ondrasik of Five for Fighting, OneRepublic, Barry Manilow and there are so many more activities planned.

Special guest hosts Nigel Lythgoe, executive producer of American Idol and So You Think You Can Dance, Richard Belzer from Law & Order: SVU,Ace Young, General Hospital’s Brandon Barash and actor/comedian John Pinette will bring their talents to the Telethon stage to help introduce some 65 performers, plus notable families served by MDA.

The Telethon will also feature cast members from the TV hits GLEE and The Doctors, Ray Romano, Patrick Duffy, Ken Howard, Lou Ferrigno and Olympic Gold medalists Bart Conner and Nadia Comaneci.

For laughs Las Vegas headliners Carrot Top, Terry Fator and George Wallace are returning along with comedic legends Norm Crosby and Charlie Callas.

So You Think You Can Dance choreographer Tyce Diorio is creating the opening number and throughout the Telethon numbers from Broadway’s Memphis, Rock of Ages and Million Dollar Quartet along with Las Vegas favs Viva Elvis by Cirque du Soleil, Paris by Night and Vegas! The Show.

Lewis will be assisted by additional co-hosts Alison Sweeney (The Biggest Loser and Days of our Lives), Former Access Hollywood host Nancy O’Dell, and former ET correspondent Jann Carl.

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research.  The Association, which is the first nonprofit to receive a Lifetime Achievement Award from the American Medical Association (“for significant and lasting contributions to the health and welfare of humanity”), also provides comprehensive health care and support services, advocacy and education.

The 2010 Jerry Lewis MDA Telethon starts, Sunday, Sept. 5th at 9 p.m. EDT.  Originating live from the South Point Hotel in Las Vegas, the show concludes Labor Day, Sept. 6th at 6:30 p.m. EDT.