Brennan (Emily Deschanel, L), her cousin Margaret (guest star Zooey Deschanel, R) and their friends celebrate Christmas together in the BONES episode "The Goop on the Girl" airing Thursday, Dec. 10 (8:00-9:00 PM ET/PT) on FOX. ©2009 Fox Broadcasting Co. Cr: Greg Gayne/FOX Copyright: Greg Gayn

Real-life sisters, Emily and Zooey Deschanel are working together on Emily’s series Bones tonight, which was especially gratifying for the two women.

Zooey is starring as Brennan’s cousin Margaret, who is celebrating the holiday season with her this year.

Both sisters have successful careers in film and on television, plus they’re good buddies too.  So, agreeing to work together was a no-brainer.

Click onto video for Emily and Zooey Deschanel’s joke-fest while discussing their joy at working together on Bones.

Bones airs 8:00 p.m. ET/PT on Fox.